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Enroll-HD study sites: 2012-2022 | Region; recruitment, tenure
Enroll-HD study sites: 2012-2022 | Region; recruitment, tenure July 26, 2023Last year, Enroll-HD celebrated the 10-year anniversary of the very first participant entering the study. To celebrate this...
View ArticleCould halting CAG expansions be a new treatment for HD?
A recent paper from a group at UMass Chan Medical School, spearheaded by Dr. Daniel O’Reilly and led by Dr. Anastasia Khvorova, used genetic strategies to lower a protein other than huntingtin. This...
View ArticleGetting to the Root of Huntington’s Disease: A Plant-Based Approach
Researchers studied a fragment of the Huntington’s disease (HD) protein in plants and found a new way to stop it from forming toxic clumps. A special plant protein that the team identified can prevent...
View ArticleBeyond huntingtin lowering: out-of-the-box approaches for the treatment of HD
In recent years, HD research headlines have trended toward huntingtin lowering: experimental therapies that target the root genetic cause of HD. But there are also several drugs in development to treat...
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Regulating repetition: Gaining control of CAG repeats could slow progression...
“Somatic expansion” is a hot topic in Huntington’s disease research. Somatic expansion is a process in which CAG repeats lengthen in some cells during aging. It’s thought to control how early HD...
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Putting it in print: GENERATION HD1 study results published
The outcomes of the GENERATION HD1 trial have just been published in a scientific journal, nearly three years after the study was halted. In March of 2021, the HD community was hit with the difficult...
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Steady progress from uniQure – promising data to end the year
With the holidays approaching, welcome news arrived on December 19th in a press release from uniQure. The latest data from the HD-GeneTRX studies of AMT-130, an experimental huntingtin-lowering gene...
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Making babies: having a family, the HD way
For people at risk of Huntington’s disease, having a baby who might inherit HD can make decisions around planning a family extremely difficult. This article explains the options available, and how...
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New HDClarity periodic dataset, PDS3, now available!
New HDClarity periodic dataset, PDS3, now available! Jan 18, 2024We are delighted to announce that the third dataset release from HDClarity, PDS3, is now available.HDClarity PDS3 contains data from...
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EHDN and Enroll-HD Congress 2024
Save the date! EHDN and Enroll-HD Congress 2024 | Sep 12-14 | Strasbourg Date of original post: Feb 13, 2024 | Date of update: N/A Event: EHDN and Enroll-HD CongressDate: September 12 to 14,...
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CRISPR-based drugs: one giant leap for mankind
You’ve likely heard of CRISPR. By now, you also may have heard that CRISPR has been used to produce a revolutionary new treatment for Sickle Cell Disease. Just 4 years after the Nobel Prize for the...
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Huntington’s Disease Therapeutics Conference 2024 – Day 1
The HDBuzz team recently convened in Palm Springs, California, along with hundreds of other scientists from all over the globe, for the 19th Annual HD Therapeutics Conference, hosted by the HD...
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